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2019年09月16日 01:56:58|来源:国际在线|编辑:大河分享
In one study published in Asian American women一个年公布的研究采访了who had previously been diagnosed with breast cancer曾被诊断为乳腺癌的were interviewed and questioned on race,美国亚裔女性 问及的问题有种族residential history, menstrual and reproductive history住宅史 月经和生育史medical and family history, anthropometrics and病历及家庭历史 身体指标cultural and religious practices.文化及宗教信仰Researchers also collected information about研究者还收集每个受访者each participants dietary intake of soy during在儿童时期 青春期 和成年时期childhood, adolescence and adulthood.饮食中对豆类的摄入To gather the most accurate information about为了收集到每个受访者the participants childhood intake of soy mothers儿童时期豆类摄入的最准确信息of participants were also questioned.他们还采访了这些受访者的母亲们In many cases mothers could not be reached,很多情况下受访者的母亲们没法联系上refused participation or had aly passed away.拒绝参加 或者已经去世In these cases only the participants data was used.这些情况下只能使用受访者自己提供的资料This chart shows the levels of intake, low, medium这张表格显示了人们在不同的and high for each stage of life;生命阶段(童年 青春期和成年后)childhood, adolescence and adulthood.对豆类不同水平的摄入情况The second column describes the ratio of participants第二栏显示了参与调查的人群中who had breast cancer cases to the controls or women乳腺癌患者人数与未患who did not have breast cancer.乳腺癌人数(即对照组)的比例The relative risk or RR for the lowest intake at each生命中每个阶段最低摄入量的stage of life is set at 1.0 and相对风险值(RR)设在1.0used as the reference value.并被当做参考值Intakes of medium or high amounts of soy are then中等量或大量豆类的摄入会和compared to 1.0. A decrease from 1.0 represents1.0相比较 低于1.0表示患病几率降低a decreased risk so the smaller the decimal in所以第三栏里的小数越小the third column the lower the risk.患癌几率越低As the chart shows increasing amounts of soy如表格显示的 在所有生命阶段里at all stages of life resulted in a decreased risk.增加豆类摄入量会使患病几率降低But the most significant decrease is seen in medium to但患病几率降低最显著的是童年时期high intakes during childhood.中等量至大量的豆类摄入This suggests that the most important time to increase这表明为了降低乳腺癌患病几率intake of soy in order to reduce risk of breast cancer而增加豆类摄入量的最重要时期is during childhood years.是童年阶段In an article published by Dr. Helferich, an associate赫尔弗里希士是伊利诺伊大学professor of nutrition at the University of Illinois and营养学副教授 研究大豆和癌症who researches soy and cancer expressed his concern他在发表的一篇文章里 表达了他对about some negative impacts大豆异黄酮在患癌几率上of soy isoflavones on cancer risk负面作用的担忧His research suggests that他的研究表明women who have estrogen sensitive breast患有雌激素敏感性乳腺癌的女性cancer or breast cancer in which estrogen encourages在雌激素的作用下 她们growth may experience increased growth of their tumors.乳腺内的肿瘤可能继续增长This is thought to be due to the fact that the这是因为异黄酮染料木素isoflavones genistein mimics the effects of estrogen和雌激素的作用相似and high levels of estrogen are associated with而且高水平的雌激素increased cancer proliferation.与癌扩散的增加有关Dr. Helferich states ;over 90% of soy consumption is赫尔弗里希士说 ;90%以上的大豆摄入likely to be a health benefit to Americans.很可能对美国人的健康有益But I am concerned about the woman with但我担心的是雌激素依赖性an estrogen-dependent cancer.乳腺癌患者She needs to be very careful about the amount她需要对她摄入的大豆异黄酮of soy isoflavones she consumes.;的量非常小心;An important note is that this study was only performed重要的一点是这项研究仅仅in animals and not in humans so it can only raise在动物身上做过 而没在人身上做过awareness of the issue not provide proof of所以这只能提高对这一问题的意识 不能negative effects of soy on cancer risk.明大豆是否对癌症患病几率有负面影响201507/386881It started life as UK 92480,这个编号为UK92480的化合物one of millions of compounds来自辉瑞制药公司的新药仓库in the stores at the drug company Pfizer.是千百万个化合物中的一员They were looking for a new drug for angina,当时专家们正在寻找治疗心绞痛的新something that would relax blood vessels一种能够放松心脏around the heart.周围血管的药物After screening hundreds of在筛查过无数的化合物之后thousands of compounds, they ended up with UK 92480.他们最终锁定了UK92480But its trials in humans were a let-down.人体实验结果却不尽如人意It was about to be consigned正当药物要被重新收回仓库时back to the stores when the trial volunteers受试者们开始不断索要药片started coming back and reporting an unusual side-effect -并反馈一种不同寻常的副作用lots of erections.阴茎勃起Add the drug the relaxations加入药物之后 其松弛度变大get larger but its trace is upside down.不过药物作用曲线却是反过来的By making a crude mock-up of the通过制作人类性器官的粗略模拟模型human sexual apparatus, senior scientist Chris Wayman高级研究员克里斯·韦曼使用了found an ingenious way to test this anecdotal evidence.一种巧妙的方法来检验这种有趣的现象201502/360080

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